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People with preexisting GI symptoms may be more prone to discomfort or intolerance, though responses vary, and formal evidence is limited

If your goal is modest, perhaps you want to reduce mindless snacking, feel more satisfied after meals, or support a dietary change that you are already committed to making, then a GLP-1 support supplement can provide a helpful nudge

[14] Other recent studies have found that vitamin D status is unaffected by metformin use, and one study found no noticeable impact of metformin on vitamin D levels at four and 16 months of use in people with type 2 diabetes

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